, improved healing, reduced health care costs, and improved patient satisfaction, but it may play a role in preventing the progression of chronic pain. 4 – 6
Opioids have traditionally been the most common analgesic for treating moderate to severe postoperative pain. 2 However, their utility is hampered by undesirable side effects, which are sometimes intolerable to the patient. These side effects include central nervous depression, respiratory depression, pruritus, nausea, vomiting, ileus, tolerance, and opioid-induced hyperalgesia. 4 – 6 By treating pain with