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We previously described the case of a patient with primary hypertension managed with telmisartan in which refractory hypotension during general anesthesia was not avoided despite withholding telmisartan for 24 hours before induction. 1 Telmisartan has the longest half-life of angiotensin receptor blockers (ARBs), and in that particular patient's case, withholding telmisartan for 5 days before a second general anesthetic positively resulted in the avoidance of severe refractory hypotension. Azilsartan has the second longest half-life of all