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Local Anesthetic Efficacy in Marijuana Users and Nonusers: A Pilot Study
Michael C. MoranDDS, MSD,
Lisa J. HeatonPhD,
Brian G. LerouxPhD, and
Natasha M. FlakeDDS, PhD, MSD
Article Category: Research Article
Volume/Issue: Volume 69: Issue 4
Online Publication Date: Dec 19, 2022
DOI: 10.2344/anpr-69-02-08
Page Range: 15 – 21

reports investigating the efficacy of local anesthetics related to marijuana use. This is surprising, given the widespread use of marijuana and continually evolving landscape of its legality at the state level within the United States. Marijuana is the most commonly used substance after tobacco and alcohol. 7 In the 2018 National Survey of Drug Abuse and Health, 34.8% of adults ages 18 to 25 and 13.3% of adults ages 26 or older had used marijuana in the past year. 7 Legalization and reduction in stigma may increase the likelihood that patients will report cannabis use

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Figure 1.; Flowchart of subject screening and testing protocol.
Michael C. Moran,
Lisa J. Heaton,
Brian G. Leroux, and
Natasha M. Flake
Figure 1.
Figure 1.

Flowchart of subject screening and testing protocol.

Figure 2.; Subject screening and participation results.
Michael C. Moran,
Lisa J. Heaton,
Brian G. Leroux, and
Natasha M. Flake
Figure 2.
Figure 2.

Subject screening and participation results.

Figure 3.; Individual data points, median, and range for dental anxiety, anesthetic onset, and anesthetic duration. There were no significant differences between the groups for Modified Dental Anxiety Scale (MDAS) scores (P = .749), anesthetic onset (P = .432), or anesthetic duration (P = .708).
Michael C. Moran,
Lisa J. Heaton,
Brian G. Leroux, and
Natasha M. Flake
Figure 3.
Figure 3.

Individual data points, median, and range for dental anxiety, anesthetic onset, and anesthetic duration. There were no significant differences between the groups for Modified Dental Anxiety Scale (MDAS) scores (P = .749), anesthetic onset (P = .432), or anesthetic duration (P = .708).

Implications of Electronic Cigarettes on the Safe Administration of Sedation and General Anesthesia in the Outpatient Dental Setting
Zachary A. HellerDO, DMD,
Edward C. Adlesic MSDMD, and
Jason E. Portnof DMDMD
Article Category: Research Article
Volume/Issue: Volume 69: Issue 2
Online Publication Date: Jul 18, 2022
DOI: 10.2344/anpr-69-02-16
Page Range: 41 – 52

JL. Cannabis, e-cigarettes and anesthesia . Curr Opin Anaesthesiol . 2020 ; 33 (3) : 318 – 326 . https://doi.org/10.1097/aco.0000000000000872 32. Chun LF, Moazed F, Calfee CS, Matthay MA

Literature Review for Office-Based Anesthesia
All summaries and comments provided by Mark A SaxenDDS, PhD
Article Category: Research Article
Volume/Issue: Volume 67: Issue 1
Online Publication Date: Jan 01, 2020
DOI: 10.2344/0003-3006-67.1.60
Page Range: 60 – 62

-Villalobos M, Todeschini A, Stoicea N, Fiorda-Diaz J, Weaver T, Bergese S. Perioperative care of cannabis users: a comprehensive review of pharmacological and anesthetic considerations. J Clin Anesthesia . 2019;57:41–49. According to the 2015 National Survey on Drug Use and Health, marijuana continues to be the most common illicit recreational drug in the United States. Cannabinoids have multisystem effects that can interfere with anesthetic agents and lead to serious consequences. This comprehensive review examines the main physiological effects of cannabinoids and