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Medical Management of Epiglottitis
Regina A. E. Dowdy DDS and
 Bryant W. Cornelius DDS, MBA, MPH
Article Category: Case Report
Volume/Issue: Volume 67: Issue 2
Online Publication Date: Jul 06, 2020
DOI: 10.2344/anpr-66-04-08
Page Range: 90 – 97

Epiglottitis is defined as inflammation of the epiglottis and/or neighboring supraglottic structures including the hypopharynx. Epiglottitis is typically caused by a bacterial infection. Historically, epiglottitis has been an infection mostly prevalent in children ages 2 to 6 years old. However, since the introduction of the Haemophilus influenzae B (HiB) vaccine, there has been a shift with increasing incidence within the adult population. Common signs and symptoms upon clinical presentation include odynophagia, dysphagia, use of the

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Figure 3. ; Classic radiographic findings. (A) Lateral radiograph of the neck revealing “thumb sign” appearance of epiglottitis. (B) Anteroposterior radiograph of the neck revealing “steeple sign” seen in croup.
Regina A. E. Dowdy and
 Bryant W. Cornelius
Figure 3. 
Figure 3. 

Classic radiographic findings. (A) Lateral radiograph of the neck revealing “thumb sign” appearance of epiglottitis. (B) Anteroposterior radiograph of the neck revealing “steeple sign” seen in croup.


Regina A. E. Dowdy and
 Bryant W. Cornelius
Figure 1. 
Figure 1. 

Computed tomography (CT) scan of the neck with contrast at time of admission. (A) Sagittal cut reveals a mass in the hypopharynx and piriform sinuses; note the limited airway space. (B) Axial cut at the level of the hyoid bone reveals a mass that is 1.4 × 0.5 cm in size. (C) Coronal cut revealing the mass intruding upon the midline of the larynx.


Regina A. E. Dowdy and
 Bryant W. Cornelius
Figure 2. 
Figure 2. 

Computed tomography (CT) scan of the neck with contrast 2 days after placement of the tracheostomy. (A) Sagittal cut reveals a mass in the hypopharynx and piriform sinuses; note the limited airway space. (B) Axial cut at the level of the hyoid bone reveals a mass that is 1.4 × 0.5 cm in size.


Robert J. Miller DO and
 Mark A. Gerhardt MD, PhD
Article Category: Other
Volume/Issue: Volume 53: Issue 1
Online Publication Date: Jan 01, 2006
Page Range: 13 – 16

Patients may cause uvula or pharyngeal injury by tooth brushing. Furthermore, the uvula may exhibit thermal trauma by contact with either very hot or very cold food and drinks. Sensory blockade of the oropharnyx may increase the susceptibility of patients to trauma. Trauma is not likely in this case because there was no airway manipulation of any kind. Uvulitis resulting from infectious agents is a rare cause of life-threatening airway obstruction. The most common cause of uvulitis is epiglottitis, and both are frequently associated with dyspnea, pharyngitis