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![<bold>Figure 1.</bold>](/view/journals/anpr/66/1/inline-i0003-3006-66-1-44-f01.png)
Effect of minute ventilation during oxygen-induced hypercapnia. During 15 minutes of high oxygen administration, which recovers substantially, is seen in patients with acute exacerbation of chronic obstructive pulmonary disease. However, the oxygen-induced hypercapnia does not recover. CO2, carbon dioxide; VE, minute ventilation.