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Perioperative Management of the Glucose-6-Phosphate Dehydrogenase Deficient Patient: A Review of Literature
Cpt Ali R. Elyassi DDS and
 Maj Henry H. Rowshan DDS
Article Category: Research Article
Volume/Issue: Volume 56: Issue 3
Online Publication Date: Jan 01, 2009
DOI: 10.2344/0003-3006-56.3.86
Page Range: 86 – 91

following is a literature review, including disease background, pathophysiology, and clinical implications, to help guide the clinician in management of the G6PD-deficient patient. METHODS A literature search was conducted in the following databases: PubMed, The Cochrane Library, Web of Science, OMIM, and Google; this was supplemented by a search for selected authors. Keywords used were glucose-6-phosphate dehydrogenase (G6PD) deficiency, anesthesia, analgesia, anxiolysis, management, favism, hemolytic anemia, benzodiazepines, codeine, codeine

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Figure 1; The hexose monophosphate shunt.
Cpt Ali R. Elyassi and
 Maj Henry H. Rowshan
Figure 1
Figure 1

The hexose monophosphate shunt.

Figure 2; Peripheral smear from a patient with Heinz body hemolytic anemia. Heinz body preparation reveals the denatured hemoglobin precipitates. (© 2007 Rector and Visitors of the University of Virginia Charles E. Hess, M.D., and Lindsey Krstic, B.A.)
Cpt Ali R. Elyassi and
 Maj Henry H. Rowshan
Figure 2
Figure 2

Peripheral smear from a patient with Heinz body hemolytic anemia. Heinz body preparation reveals the denatured hemoglobin precipitates. (© 2007 Rector and Visitors of the University of Virginia Charles E. Hess, M.D., and Lindsey Krstic, B.A.)

Figure 3; High-power view of a normal peripheral blood smear. The red cells are of relatively uniform size and shape. A lymphocyte can also be seen. The diameter of the normal red cell should approximate that of the nucleus of the small lymphocyte. (© 2007 Rector and Visitors of the University of Virginia Charles E. Hess, M.D., and Lindsey Krstic, B.A.)
Cpt Ali R. Elyassi and
 Maj Henry H. Rowshan
Figure 3
Figure 3

High-power view of a normal peripheral blood smear. The red cells are of relatively uniform size and shape. A lymphocyte can also be seen. The diameter of the normal red cell should approximate that of the nucleus of the small lymphocyte. (© 2007 Rector and Visitors of the University of Virginia Charles E. Hess, M.D., and Lindsey Krstic, B.A.)

General Anesthesia in a Glucose-6-Phosphate Dehydrogenase Deficiency Child: A Case Report
Takahiro Goi DDS,
 Yoshiki Shionoya DDS, PhD,
 Katsuhisa Sunada DDS, PhD, and
 Kiminari Nakamura DDS, PhD
Article Category: Case Report
Volume/Issue: Volume 66: Issue 2
Online Publication Date: Jan 01, 2019
DOI: 10.2344/anpr-66-01-05
Page Range: 94 – 96

, Meloni T. Favism: disordered erythrocyte calcium homeostasis . Blood . 1985 ; 66 : 294 – 297 . 4 Lau HK, Li CH, Lee AC. Acute massive haemolysis in children with glucose-6-phosphate dehydrogenase deficiency . Hong Kong Med J . 2006 ; 12 : 149 – 151