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Hallucinations and Delirium in the Dental Office Following Triazolam Administration
Jason H. GoodchildDMD and
Mark DonaldsonPharmD
Article Category: Research Article
Volume/Issue: Volume 52: Issue 1
Online Publication Date: Mar 01, 2005
DOI: 10.2344/0003-3006(2005)52[17:HADITD]2.0.CO;2
Page Range: 17 – 20

the literature illustrates several cases of hallucinations involving the accepted indication (insomnia) of triazolam. In 1979, van der Kroef 4 described triazolam as potentiating a “syndrome” that included reactions such as “depersonalisation, derealisation, depression, and hypnagogic hallucinations.” Although van der Kroef was criticized for the lack of validity of his claims, his accounts marked the beginning of controversy involving triazolam and delirium. 4 5 Delirium involves a failure of cognitive function characterized by confusion, disordered speech

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Atsuki YamaguchiDDS,
Yuki KojimaDDS, PhD, and
Kazuya HirabayashiMD, MBA
Article Category: Brief Report
Volume/Issue: Volume 70: Issue 2
Online Publication Date: Jun 28, 2023
Page Range: 88 – 90

helps minimize the risk of associated postoperative complications. Potential problems related to NSAIDs may include gastrointestinal and cardiovascular disorders, impaired platelet function, and renal issues, while opioids can cause nausea/vomiting, constipation, drowsiness, delirium/hallucinations, respiratory depression, and hyperalgesia. 3 Patient recovery from surgery and their prognosis are more favorable in the absence of such complications. Ropivacaine has 2 major advantages when used for a nerve block: a prolonged analgesic effect (12-24 hours) and

David B. GuthrieDMD,
Martin R. BoorinDMD,
Andrew R. SistiBA,
Ralph H. EpsteinDDS,
Jamie L. RomeiserMPH,
David K. LamMD, DDS, PhD,
Tong J. GanMD, MBA, MHS, and
Elliott Bennett-GuerreroMD
Article Category: Research Article
Volume/Issue: Volume 68: Issue 1
Online Publication Date: Apr 07, 2021
Page Range: 3 – 9

, combative and violent behavior may pose a physical danger to the patient, caretakers, and the anesthesia care team. The use of intramuscular (IM) sedative agents, which does not require patient cooperation, can facilitate an efficient transfer to the OR and induction of GA. Although IM ketamine is effective and commonly used for the management of special need patients, it has numerous undesirable side effects including dysphoria, hypersalivation, hyperreactive airway reflexes, hypertension, tachycardia, muscle hypertonia, hallucinations, increased incidence of

Joel M. WeaverDDS, PhD
Article Category: Other
Volume/Issue: Volume 60: Issue 4
Online Publication Date: Jan 01, 2013
Page Range: 143 – 144

substitute for local anesthetic. Patients were technically conscious, highly analgesic, and well oxygenated, but the high concentrations of nitrous oxide produced a significant percentage of patients with nausea, vomiting, and hallucinations. The Langa nitrous oxide analgesia technique was ultimately modified to what became known as nitrous oxide–oxygen conscious sedation and is currently known as nitrous oxide–oxygen minimal sedation. With this technique, the nitrous oxide is typically carefully titrated to a concentration of 50% or less in combination with oxygen and is

Masatoshi FujitaDDS, PhD and
Kentaro MizutaDDS, PhD
Article Category: Case Report
Volume/Issue: Volume 69: Issue 1
Online Publication Date: Apr 04, 2022
Page Range: 39 – 41

, irritability, mutism, aggressiveness, derealization, hallucinations, and delusions); (2) hyperphagia with compulsive eating; (3) hypersexuality with inappropriate or odd behavior; and (4) abnormal behavior such as irritability, aggression, and odd behavior. 6 In accordance with these diagnostic criteria, this patient was diagnosed with KLS when she was 13 years old, presenting with recurrent episodes of hypersomnia and hyperphagia lasting for 6 to 10 days. This patient reported taking no medications to treat her KLS-related symptoms. Although several medications

Yoshiki ShionoyaDDS, PhD,
Hatsuko KamigaDDS,
Gentarou TsujimotoDDS, PhD,
Eishi NakamuraDDS,
Kiminari NakamuraDDS, PhD, and
Katsuhisa SunadaDDS, PhD
Article Category: Case Report
Volume/Issue: Volume 67: Issue 1
Online Publication Date: Jan 01, 2020
Page Range: 28 – 34

as emergence delirium, hallucinations, nausea, or vomiting, noted. She was able to walk 150 minutes after cessation of anesthesia and was subsequently discharged at that time. Her OAA/S scores, vital signs (BP, HR, Sp o 2 , and RR), and total doses of anesthetic agents are summarized in Table 2 . The total operating time was 40 minutes, the total anesthesia time was 58 minutes, the emergence time was 74 minutes, and the recovery time was 150 minutes. Table 2 OAA/S Scale, Vital Signs, and Total Dosages

Annie HuangDMD and
Thomas TanbonliongDDS
Article Category: Research Article
Volume/Issue: Volume 62: Issue 3
Online Publication Date: Jan 01, 2015
Page Range: 91 – 99

intraoperative adverse event to be hallucination (3.9%), while the most common postdischarge adverse event was excessive sleep (41.9%) with moderate sedation involving chloral hydrate or midazolam. This study also found that minor adverse events were significantly more likely with high oral doses of choral hydrate than with midazolam. 8 Because oral liquid chloral hydrate has been discontinued by its manufacturer, further investigation of patient discharge parameters of other oral sedation regimens is warranted. Research is needed to evaluate the recovery period of patients

Kyle J. KramerDDS, MS,
Steven GanzbergDMD, MS,
Simon PriorBDS, PhD, MS, and
Robert G. RashidDDS, MAS
Article Category: Other
Volume/Issue: Volume 59: Issue 3
Online Publication Date: Jan 01, 2012
Page Range: 107 – 117

remifentanil group was 24.7 ± 7.6 minutes, and mean recovery time was 42.9 ± 18.7 minutes for the ketamine group, a difference of 18.2 minutes ( P = .0004). Additionally, none of the participants reported any negative behavioral effects such as dysphoria or hallucinations. Satisfaction Surveys The results of the patient and surgeon satisfaction surveys were evaluated using the Fisher exact test ( Table 6 ). The 5-point Likert scale used the following points to measure patient satisfaction with the sedation: 1 indicated “very satisfied”; 2

Zakaria MessiehaDDS
Article Category: Other
Volume/Issue: Volume 60: Issue 2
Online Publication Date: Jan 01, 2013
Page Range: 67 – 71

potential for causing emergence hallucinations and lowering the seizure threshold in highly seizure-prone individuals. However, both of these undesirable side effects have been linked to ketamine administration at much higher doses than what was reported in the literature to help eliminate EAD. Prolongation of recovery time often associated with higher doses of ketamine should not be a concern with the dose in the above-mentioned study. Nevertheless, 16.5% still represents a high incidence of EAD. ALFENTANIL Kim et al 8 studied the

David B. GuthrieDMD,
Ralph H. EpsteinDDS,
Martin R. BoorinDMD,
Andrew R. SistiBA,
Jamie L. RomeiserMPH, and
Elliott Bennett-GuerreroMD
Article Category: Research Article
Volume/Issue: Volume 69: Issue 2
Online Publication Date: Jul 18, 2022
Page Range: 17 – 23

suggests midazolam 0.1 to 0.15 or ketamine 2 to 3 mg/kg with atropine 0.02 mg/kg. 5 Miller's Anesthesia suggests ketamine 4 to 5 mg/kg IM for reduction of anxiety and 5 to 10 mg/kg to induce general anesthesia. 6 Furthermore, this text also suggests IM coadministration of a benzodiazepine to reduce hallucinations and an anticholinergic to reduce sialorrhea but specifies neither specific agents nor dosages. Basics of Anesthesia recommends ketamine 5 mg/kg and notes that IM atropine or glycopyrrolate can be used (but does not specify an anticholinergic dose). 7