Figure 2 a R/L value (%) Figure 2b I/R value (%)
a) R/L value (%), showing the risk area for ischemia expressed as a percentage of the left ventricle. After the completion of each measurement, the risk area for ischemia was determined by injecting 10% Evans Blue dye via the jugular vein following LAD re-occlusion. Statistical comparisons of the R/L values among the groups were made using the Kruskal-Wallis test, followed by Dunn's procedure. Data are reported as the group mean ± SEM (n = 8), and probability values (p) less than 0.05 were considered statistically significant. The R/L values ranged from 39.8 ± 3.9% to 48.7 ± 4.3% and revealed no significant differences among the groups, suggesting that the changes in the infarct size observed among the groups did not depend on the R/L.
b) I/R value (%), showing the infarct size expressed as a percentage of the risk area for ischemia. Statistical comparisons of the I/R values among the groups were made using the Kruskal-Wallis test, followed by Dunn's procedure. Data are reported as the group mean ± SEM (n = 8), and probability values (p) less than 0.05 were considered statistically significant. The I/R value was 49.7 ± 5.7% in the Control group ; the I/R values decreased significantly to 31.3 ± 8.2% in the Pre group, 16.5 ± 7.4% in the Post group, and 19.0 ± 9.1% in the Pre + Post group.
*Significant difference (p<0.05) compared with the Control group.
#Significant difference (p<0.05) compared with the Pre group.