Epinephrine, a vasoconstrictor, is often added to local anesthetics for dental use to enhance and prolong the local anesthetic effect, prevent local anesthetic systematic toxicity, and impart a hemostatic effect. 1 Epinephrine-containing local anesthetics are commonly used for surgical procedures involving the oral cavity and facial bones, such as tooth extraction, radicular cystectomy, implant placement, and jawbone resection. 2 – 5 The vasoconstrictive effect of epinephrine in the maxilla and mandible has not been sufficiently described