Search Results

brain natriuretic hormone level (47 pg/mL). An electrocardiogram obtained 1 month before surgery demonstrated prolongation of the corrected QT interval (QTc) of 529 ms using the Bazett formula (QTc = QT time/√RR interval) with flat or inverted T waves in all leads. He was suspected of having long-QT syndrome (LQTS) according to the diagnostic criteria (score: 3) of Schwartz and Crotti. 3 No major genetic abnormalities associated with LVNC were detected in his family, and the cause of the QT prolongation in this patient was not clear. However, it was reported that a

measured in seconds): 2 When analyzing QTc, one finds that the normal values for men and women are slightly different. This has been attributed to females' showing a slightly longer baseline QTc than men in clinical and animal trials. In general, it is accepted that a value of QTc greater than 0.440 seconds is considered prolonged; however, more specific values as they apply to LQTS have been identified (Table 1 ). 3 These values are based on corrections derived from Bazette's formula because this formula has been more widely used and

glycopyrrolate for neuromuscular block reversal. Patient 2 was a previously healthy 21-year-old female who developed AV-dissociation following reversal, which the authors attributed to the ineffectiveness of glycopyrrolate to overcome a combination of cardiac conduction-depression provoked by the cumulative drug interaction due to combination of midazolam, fentanyl, propofol, ranitidine, and neostigmine. 2 Patient 3, a morbidly obese patient, developed second-degree AV-block and Q-Tc prolongation following reversal, which responded to atropine. Morbid obesity, female gender

. Transferring the patient from the office to the ambulance consumed about 15 minutes, with an additional 15 minutes for transport to the emergency room. The dentist anesthesiologist continued to have primary responsibility for airway maintenance until the patient was accepted by emergency room personnel. At the hospital, initial laboratory testing, including a chemistry 8 panel and complete blood count, was obtained and soon interpreted as within normal limits. A 12-lead ECG showed no signs of ST segment elevation or depression, and only a minor QT(c) prolongation of

generated by oxidation of its alcohol moiety to a carboxylic acid. 27 Hydroxyzine is relatively fast acting with an onset that occurs between 15 and 60 minutes and a duration of action between 4 to 6 hours. The sedative properties of hydroxyzine occur at the subcortical level of the CNS. 19 Hydroxyzine is reported to prolong the QT/QTc interval based on postmarketing reports of rare events of torsade de pointes, cardiac arrest, and sudden death and should be used with caution in patients with an increased baseline risk for QTc prolongation properties. 19

branch block, QTc prolongation (513 ms), and occasional premature ventricular contractions. Her hyperlipidemia and gastroesophageal reflux disease were adequately controlled with oral medications. Her diabetes was well controlled with oral medications, with a preoperative HbA1c of 5.9. The patient experienced chronic dyspnea during mild-to-moderate exertion but denied previous use of supplemental oxygen. She had no history of smoking and was noncompliant with her home continuous positive airway pressure machine. The patient's medications at the time of

laparoscopic surgery and rapidly stabilized following the administration of sugammadex. 29 In that case, the anaphylaxis was unresponsive to epinephrine, crystalloid fluids, and prolonged cardiopulmonary resuscitation. 29 Dysrhythmias.  A few reports of QTc interval prolongation, atrioventricular block, and even cardiac arrest after sugammadex exist. It is postulated that the maintenance anesthetic agents propofol or sevoflurane could have been contributory; however, the mechanism for this vagal effect is not yet fully understood