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Yoshiki ShionoyaDDS, PhD,
Maki YamamotoDDS,
Katsuhisa SunadaDDS, PhD, and
Kiminari NakamuraDDS, PhD
Article Category: Research Article
Volume/Issue: Volume 67: Issue 1
Online Publication Date: Jan 01, 2020
Page Range: 45 – 47
RASopathies, a family of developmental disorders with overlapping phenotypic similarities; other noted RASopathies include Noonan and Costello syndromes. Gene mutations in RASopathies inhibit myoblast differentiation, resulting in fewer myosin heavy chains and eventually abnormal muscle fiber size and variability. All RASopathies present with musculoskeletal manifestations, including muscle weakness and decreased muscle mass, but they are particularly prominent in CFC syndrome. 4 Recovery from anesthesia is faster with the use of desflurane rather than other inhalation