Time course of experiment 1. Mean arterial pressure (MAP), heart rate (HR), central venous pressure (CVP), end-tidal CO2 (ETCO2), and palatal mucosal blood flow (PMBF) were measured in both groups at 12, 17, 22, 27, 32, and 42 minutes after administration of 0.2 mg/kg midazolam, 0.05 mg/kg butorphanol, and 2 mg/kg rocuronium (time 0). The SMB group was maintained with sevoflurane in oxygen. The DMB group was maintained with dexmedetomidine. SMB indicates sevoflurane, midazolam, and butorphanol; DMB, dexmedetomidine, midazolam, and butorphanol.