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![Figure 2.](/view/journals/anpr/52/1/inline-i0003-3006-52-1-12-f02.gif)
General anesthesia was induced with 5% sevoflurane in 67% nitrous oxide and 33% oxygen, and then maintained with a continuous infusion of 6–12 mg/kg propofol per hour and 0.5–1.5% sevoflurane in 67% nitrous oxide and 33% oxygen.
![Figure 1.](/view/journals/anpr/63/1/inline-i0003-3006-63-1-17-f01.png)
Method of general anesthesia. General anesthesia was induced by oxygen 5 L/min and 5% sevoflurane, and then a tracheotomy was performed, after which general anesthesia was maintained at oxygen 3 L/min and 3% sevoflurane. A cannula was inserted into the femoral artery, and arterial pressure was continuously recorded throughout the experiment using a polygraph and a pressure transducer.
![<bold>Figure 1</bold>](/view/journals/anpr/63/3/inline-i0003-3006-63-3-131-f01.png)
Method of general anesthesia. General anesthesia was induced by oxygen 5 L/min and 5% sevoflurane, and then a tracheotomy was performed, after which general anesthesia was maintained at oxygen 3 L/min and 3% sevoflurane. A cannula was inserted into the femoral artery, and arterial pressure was continuously recorded throughout the experiment using a polygraph and a pressure transducer.
![<bold>Figure 2.</bold>](/view/journals/anpr/65/3/inline-i0003-3006-65-3-168-f02.png)
Time course of experiment 1. Mean arterial pressure (MAP), heart rate (HR), central venous pressure (CVP), end-tidal CO2 (ETCO2), and palatal mucosal blood flow (PMBF) were measured in both groups at 12, 17, 22, 27, 32, and 42 minutes after administration of 0.2 mg/kg midazolam, 0.05 mg/kg butorphanol, and 2 mg/kg rocuronium (time 0). The SMB group was maintained with sevoflurane in oxygen. The DMB group was maintained with dexmedetomidine. SMB indicates sevoflurane, midazolam, and butorphanol; DMB, dexmedetomidine, midazolam, and butorphanol.