withdrawal symptoms such as hyperarousal, irritability, insomnia, flulike symptoms, nausea, myalgias, paresthesias, dizziness, and visual disturbances. 6 If an overdose of SSRIs occurs, it is rarely fatal, and serotonin syndrome (discussed in part II) may occur. 6 , 15 SSRIs are usually continued during the perioperative period and do not have the same hemodynamic concerns as TCAs, SNRIs, or MAOIs with respect to the concomitant use of direct- or indirect-acting sympathomimetics. 7
Serotonin-Norepinephrine Reuptake Inhibitors
The SNRIs