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Figure 1. ; Selection criterion and breakdown of study cases. Of the 791 patients who underwent general anesthesia with total intravenous anesthesia (TIVA) using propofol, fentanyl, and remifentanil, 761 patients without any of the exclusion criteria were enrolled. A total of 121 patients had postoperative nausea and vomiting (PONV), whereas 640 did not.
Emi Ishikawa,
Rie Iwamoto,
Takayuki Hojo,
Takahito Teshirogi,
Keiji Hashimoto,
Makiko Shibuya,
Yukifumi Kimura, and
Toshiaki Fujisawa
<bold>Figure 1.</bold>
Figure 1.

Selection criterion and breakdown of study cases. Of the 791 patients who underwent general anesthesia with total intravenous anesthesia (TIVA) using propofol, fentanyl, and remifentanil, 761 patients without any of the exclusion criteria were enrolled. A total of 121 patients had postoperative nausea and vomiting (PONV), whereas 640 did not.


Emi Ishikawa,
Rie Iwamoto,
Takayuki Hojo,
Takahito Teshirogi,
Keiji Hashimoto,
Makiko Shibuya,
Yukifumi Kimura, and
Toshiaki Fujisawa
<bold>Figure 2.</bold>
Figure 2.

Risk factors for postoperative nausea and vomiting (PONV; 0–24 h) after intubated general anesthesia using total intravenous anesthesia (TIVA). Arrows illustrate factors with increased PONV risk. Arrow thickness illustrates size of the factor's adjusted odds ratio (OR) per study data. The strongest PONV risk factor was bimaxillary osteotomy (OR 5.69) followed by female sex (OR 2.73) and sagittal split ramus osteotomy (SSRO; OR 2.28). Factors lacking arrows were not significantly associated with PONV.


Comparison of Propofol-Remifentanil Versus Propofol-Ketamine Deep Sedation for Third Molar Surgery
Kyle J. KramerDDS, MS,
Steven GanzbergDMD, MS,
Simon PriorBDS, PhD, MS, and
Robert G. RashidDDS, MAS
Article Category: Other
Volume/Issue: Volume 59: Issue 3
Online Publication Date: Jan 01, 2012
DOI: 10.2344/12-00001.1
Page Range: 107 – 117

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Emi IshikawaDDS,
Rie IwamotoDDS, PhD,
Takayuki HojoDDS, PhD,
Takahito TeshirogiDDS,
Keiji HashimotoDDS,
Makiko ShibuyaDDS, PhD,
Yukifumi KimuraDDS, PhD, and
Toshiaki FujisawaDDS, PhD
Article Category: Research Article
Volume/Issue: Volume 69: Issue 1
Online Publication Date: Apr 04, 2022
Page Range: 18 – 23

17 studies on the incidence of PONV after general anesthesia maintained with propofol vs volatile agents, propofol was significantly lower (median incidence 13.3% vs 25%). 5 Although total intravenous anesthesia (TIVA) may have a lower incidence, PONV can still occur. Therefore, intervention to further reduce PONV risk may be needed even in TIVA cases. Although reports have identified patient-, surgery-, and anesthesia-specific factors related to PONV, 3 , 4 , 7 – 10 none have focused only on TIVA cases. The purpose of this study was to determine whether the

Airi Sakamizu,
Erika Yaguchi, and
Shinsuke Hamaguchi
Article Category: Brief Report
Volume/Issue: Volume 67: Issue 4
Online Publication Date: Dec 31, 2020
Page Range: 233 – 234

for palatoplasty at 3 years of age, she experienced intraoperative metabolic acidosis, hypoglycemia, and fever up to 40°C, along with postoperative elevation of creatine phosphokinase. However, the hyperthermia resolved without any treatment. The patient subsequently underwent fistula closure at 12 years of age under general anesthesia with total intravenous anesthesia (TIVA) using remifentanil and propofol without any adverse events. Accordingly, we suspected a potential history of malignant hyperthermia, possibly triggered by muscle glycogen storage disease (GSD-0

Michelle WongDDS, MSc
Article Category: Case Report
Volume/Issue: Volume 64: Issue 4
Online Publication Date: Jan 01, 2017
Page Range: 244 – 247

regurgitated clear liquids are likely to represent little risk of aspiration morbidity. 6 Furthermore, aspiration requires something in the proximal gastrointestinal tract. 6 Given that this patient had surgically cured SMAS, behavioral supragastric belching reduced by anxiolytics, controlled GERD, and prolonged fasting time, it was decided that she could undergo the nonintubated total intravenous anesthesia (TIVA) deep sedation routinely practiced at this hospital outpatient ambulatory dental clinic. Endotracheal intubation would be another airway management

Yoshio HayakawaDDS, PhD,
Keiko Fujii-AbeDDS, PhD,
Sayaka AkitomiDDS,
Shihomi NiwaDDS,
Michiru AbeDDS,
Manami OtsukaDDS, PhD,
Maho IkedaDDS,
Takumi IshikawaDDS, PhD,
Manami YajimaDDS, PhD, and
Hiroshi KawaharaDDS, PhD
Article Category: Research Article
Volume/Issue: Volume 70: Issue 4
Online Publication Date: Jan 15, 2024
Page Range: 159 – 167
Article Category: Other
Volume/Issue: Volume 59: Issue 4
Online Publication Date: Dec 01, 2012
Page Range: 172 – 172

Sympathomimetics, 159 Techniques, 127 TIVA, 107 Vibrating-mesh, 123 Volatile anesthetics, 154 Warming, 127

Mark A. SaxenDDS, PhD
Article Category: Review Article
Volume/Issue: Volume 70: Issue 1
Online Publication Date: Mar 28, 2023
Page Range: 49 – 50

children, ages 6 months to 7 years, tested the hypothesis that total intravenous anesthesia (TIVA) with propofol was superior to sevoflurane in providing optimal conditions for LMA removal during emergence. Patient were randomly assigned equally to receive either TIVA with propofol or sevoflurane. In both groups, patients were mechanically ventilated. At the end of the procedure, LMAs were removed when patients were physiologically and neurologically recovered to a degree to permit a safe, natural airway. The primary aim of this study was to compare the occurrence of at

Mark A. SaxenDDS, PhD,
Richard D. UrmanMD, MBA, and
Joseph T. HomsiMD
Article Category: Research Article
Volume/Issue: Volume 66: Issue 2
Online Publication Date: Jan 01, 2019
Page Range: 111 – 114

, studies with insufficient information or data, and studies focused on other outcomes, they deemed 1 prospective randomized controlled trial and 9 retrospective studies eligible for analysis. The primary outcome measures were recurrence-free survival and overall survival. Patients receiving propofol or remifentanil infusion during their surgery were included in the total intravenous anesthesia (TIVA) group; patients receiving sevoflurane, isoflurane, desflurane, or enflurane were included in the volatile group. Collectively, the analysis examined over 21,000 cancer