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Recently, intranasal dexmedetomidine (DEX) has been reported to be effective as an anesthesia premedication. 1 However, most studies involved healthy pediatric patients, and none involved adult patients. We present a case report in which premedication using intranasal DEX was successfully performed for an adult patient with intellectual disability (ID). CASE PRESENTATION The patient was a 27-year-old woman (height, 150 cm; weight, 48.5 kg; body mass index, 21.6 kg/m 2 ) with ID, epilepsy, and autism spectrum disorder who was scheduled for dental

inhalation, can be very stressful. If the patient is unable to cooperate, physical restraint may be necessary, potentially leading to problematic psychological and/or physical insult. Efforts to mitigate these adverse effects can include preanesthetic medications, 2 which can be administered via several methods depending on the degree of patient cooperation and acceptance. Patients who are fearful or overly alert may have difficulty accepting premedication. In the present case, we initially planned to use deep IV sedation (IVS) to treat a patient with severe

The induction of intravenous conscious sedation in pediatric patients undergoing extensive dental treatment may be a challenge, particularly during parental separation and venipuncture. The use of sedative premedication may help reduce the anxiety and minimize psychological trauma in these patients. Midazolam (Versed, Hoffman-La Roche Inc, Nutley, NJ) is an example of such a preoperative sedative agent. As a water-soluble benzodiazepine, midazolam is nonirritating and has anxiolytic, sedative, hypnotic, and amnesic properties. Midazolam has been used as a

%, indicating enlargement of the cardiac silhouette, and there was diaphragmatic eventration, which was thought to be congenital. An electrocardiogram showed normal sinus rhythm with a heart rate of 102 beats/min. There were no obvious cardiac function abnormalities on echocardiography. Therefore, the patient had most of the features of the MELAS syndrome. Midazolam (10 mg) was administered orally as premedication 30 minutes before anesthetic induction, but the patient was uncooperative, and his body movements were difficult to control upon entering the operating room

maintained with total intravenous anesthesia consisting of remifentanil and propofol. Patients were excluded as study subjects if they were hospitalized or sedative premedication was needed. Variables Predictor variables were gender, valproic acid (yes or no), phenytoin (yes or no), clobazam (yes or no), carbamazepine (yes or no), clonazepam (yes or no), phenobarbital (yes or no), zonisamide (yes or no), sevoflurane use for induction (yes or no), tooth extraction (yes or no), age, body mass index, propofol rate (μg/kg body weight

Heller ZA, Adlesic EC, Portnof JE. Implications of electronic cigarettes on the safe administration of sedation and general anesthesia in the outpatient dental setting. Anesth Prog . 2022;69(2):41–52. In the Discussion section, an incorrect dosage was given in the following sentence: “The IV premedication dosage is 0.33–0.67 mg/kg, while the IM premedication dosage is 2.5 lg/kg, either route should be administered 15 minutes prior to procedure start.” The online version has been corrected to read “0.33–0.67 μg/kg…”

. Pediatric Anesthesia Trends in the practice of parental presence during induction of anesthesia and the use of preoperative premedication in the United States, 1995–2002: results of a follow-up national survey Abstract In a repeat of a 1995 survey that indicated that most children were taken into the operating room without a sedative premedication or the presence of parents, this follow-up study was conducted in 2002 by initially targeting 5000 anesthesiologists. The results demonstrated a change in practice with