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Abstract

The role of temperature in the action of local anesthetics was studied in 20 healthy young volunteers with plain 3% mepivacaine injected periapically twice in their maxillary first premolar, the first time with the solution at a temperature of 20°C and the second time at 4°C. The pulpal response was measured with a pulp tester every minute. The onset of pulp anesthesia was found to be of no statistical difference between 20°C and 4°C. On the other hand, mepivacaine at a temperature of 4°C was found to have a statistically significant longer duration of action. Our conclusion is that the drop in temperature of mepivacaine from 20°C to 4°C provides a longer duration of pulpal anesthesia.

Keywords: Temperature; Mepivacaine; Local anesthesia; Mechanism of action, onset, duration
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Copyright: © 2006 by the American Dental Society of Anesthesiology
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Article Contents

Comparison of Remimazolam and Propofol for Intubated General Anesthesia for Oral and Maxillofacial Surgery

Yoshio Hayakawa DDS, PhD,
 Keiko Fujii-Abe DDS, PhD,
 Sayaka Akitomi DDS,
 Shihomi Niwa DDS,
 Michiru Abe DDS,
 Manami Otsuka DDS, PhD,
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 Takumi Ishikawa DDS, PhD,
 Manami Yajima DDS, PhD, and
 Hiroshi Kawahara DDS, PhD

The Impact of COVID-19 on Dental Anesthesiologists: An Online Survey of Board-Certified Dental Anesthesiology Specialists of the Japanese Dental Society of Anesthesiology

Takuro Sanuki DDS, PhD,
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 Shota Tsukimoto DDS, PhD,
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