Editorial Type:
Article Category: Research Article
 | 
Online Publication Date: Jan 01, 2007

The Recognition, Physiology, and Treatment of Medication-Induced Methemoglobinemia: A Case Report

DDS, MD,
DMD, MD, and
DMD
Page Range: 115 – 117
DOI: 10.2344/0003-3006(2007)54[115:TRPATO]2.0.CO;2
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Abstract

Dapsone is a leprostatic agent commonly prescribed for the management of leprosy, malaria, and the immunosuppression-induced infections of Pneumocystis carinii and Toxoplasma gondii. In susceptible patients, methemoglobinemia, a potentially life-threatening event, can occur. We report a case of dapsone-induced methemoglobinemia which was observed during general anesthesia for the management of a fractured mandible. The pathophysiology, diagnosis, and management of dapsone-induced methemoglobinemia will be discussed.

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Copyright: © 2007 American Dental Society of Anesthesiology

Contributor Notes

Address correspondence to Dr Turner, Department of Oral and Maxillofacial Surgery, NYU College of Dentistry, 345 E 24th St, New York, NY 10010-4086; mdt4@nyu.edu.
Received: May 30, 2006
Accepted: Jun 01, 2007