Editorial Type:
Article Category: Other
| Online Publication Date: Jan 01, 2015
Anaphylactoid-like Reaction to Midazolam During Oral and Maxillofacial Surgery
Anaphylactoid-like Reaction to Midazolam During Oral and Maxillofacial Surgery
DDS,
DDS, PhD, and
DDS, PhD
Page Range: 64 – 65
We experienced a case of life-threatening hypotension and bronchoconstriction associated with edema in a patient undergoing resection of a tumor of the right mandible following intravenous midazolam for induction of general anesthesia. We decided to postpone surgery for further examination of a possible drug-induced allergic reaction, and we rescheduled surgery for 1 week later. After administering H1 and H2 histamine antagonists, we administered a slow induction with sevoflurane in nitrous oxide and oxygen plus intravenous atropine sulfate after performing a test dose injection. We safely induced and maintained anesthesia with nitrous oxide, oxygen, and sevoflurane.Abstract
Keywords: Midazolam; Anaphylactoid reaction
Copyright: © 2015 by the American Dental Society of Anesthesiology
Contributor Notes
Address correspondence to Dr Terumi Ayuse, Department of Clinical Physiology, Nagasaki University Graduate School of Biomedical Science, 1-7-1 Sakamoto Nagasaki-shi, 852-8588, Japan; ayuse@nagasaki-u.ac.jp.
Received: Sep 03, 2014
Accepted: Jan 10, 2015