The majority of the readers of Anesthesia Progress provide ambulatory anesthesia and sedation in the office-based setting. Unlike a hospital or surgery center, we personally provide or supervise all perioperative care, including postanesthesia/sedation instructions. With our current intravenous agents, we are so used to rapid recovery and discharge that many of us routinely tell our patients that by the next day, they will be fully recovered. But, can we be so certain this is true?

Much attention has recently focused on the possible neurotoxicity of sedative and anesthetic agents in very young children. Issues of sometimes subtle behavioral